WebRed-Al ® sodium bis(2-methoxyethoxy)aluminum hydride [NaAlH 2 (OCH 2 CH 2 OCH 3) 2] is used as a versatile reducing agent in organic synthesis.It is used to reduce: Aldehydes, ketones, esters, and anhydrides to primary alcohols. Ketoximes and aldoximes to primary amines. Cyclic compounds such as lactones and epoxides to diols. WebEfficient preparation of chiral diamines via Red-Al reduction of N-Boc-protected amino acid-derived secondary amides. Tetrahedron Letters 2006, 47 (11) , 1717-1720. DOI: 10.1016/j.tetlet.2006.01.056. Jasper Kaiser, Sape S. Kinderman, Bart C. J. van Esseveldt, Floris L. van Delft, Hans E. Schoemaker, Richard H. Blaauw, Floris P. J. T. Rutjes. .
Reduction of nitro compounds - Wikipedia
WebJun 27, 2006 · The aim of this paper is to explore a facile, rapid and scalable method for the exfoliation and reduction of graphene oxide (GO). In this work, the GO was reduced within 30 min using Red Al as a ... WebRed-Al ®, or sodium bis(2-methoxyethoxy)aluminum dihydride (Vitride ®, SMEAH), is a versatile reducing agent and a good substitute for LiAlH 4 in many reactions. Red-Al ® is nonpyrophoric, although still moisture-sensitive, and is available in solution, allowing for easier handling compared to LiAlH 4.. Red-Al ® is particularly effective at the reduction of … photon change hostname
Use of DOE for Rapid Development of a Red-Al Reduction Process …
WebRed-Al is an efficient chelation-controlled reducing reagent for acyclic acetal-protected R -hydroxy ketones. Typically, high diastereomeric ratios and yields can be achieved for the … WebAug 25, 2004 · A Red-Al reduction process was successfully scaled to produce multikilogram quantities of 1, thus demonstrating a safer and more economical process. Further development resulted in an optimized procedure, which not only avoided borane reduction but… View via Publisher organica1.org Save to Library Create Alert Cite Figures … WebApr 1, 2010 · The reduction presumably occurs by formation of an aluminum complex of the propargylic alcohol and subsequent delivery of hydride in an S N2′fashion. (E) Ghosh et al.9 used Red-Al reg;... how much are platinum rings